Gene
ccdc80
- ID
- ZDB-GENE-030616-56
- Name
- coiled-coil domain containing 80
- Symbol
- ccdc80 Nomenclature History
- Previous Names
-
- si:bz20i5.2
- ssg1 (1)
- zgc:113236
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Involved in regulation of systemic arterial blood pressure and somitogenesis. Predicted to localize to extracellular region. Used to study pulmonary hypertension. Is expressed in several structures, including cardiovascular system; mesonephric duct; nervous system; pleuroperitoneal region; and solid lens vesicle. Orthologous to human CCDC80 (coiled-coil domain containing 80).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6912708 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| pulmonary hypertension | y1Tg + CRISPR1-ccdc80 | standard conditions | Sasagawa et al., 2016 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR025232 | Domain of unknown function DUF4174 |
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF4174 |
|---|---|---|
|
UniProtKB:B7SDQ7
|
867 | |
|
UniProtKB:Q90X49
|
867 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ccdc80-201
(1)
|
Ensembl | 2,604 nt |
Interactions and Pathways
No data available
Plasmids
No data available